Myristoyl Pentapeptide-17

肉豆蔻酰五肽-17

肉豆蔻酰五肽-17

Myristoyl pentapeptide-17 is a bioactive peptide specifically designed and synthesized to address the insufficient growth of natural eyelashes/hair.

 

 

SKU: 198854 分类:
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Myristoyl pentapeptide-17 is a bioactive peptide specifically designed and synthesized to address the insufficient growth of natural eyelashes/hair.

Derived from a 14-18 氨基酸 fragment of human keratin-associated protein KAP5-1, it undergoes N-terminal 肉豆蔻酰化 and C-terminal amidation; this enhances its half-life, allowing for direct penetration of human epidermal 细胞膜.

Myristoyl pentapeptide-17 is currently one of the more potent cosmetic peptides used to stimulate eyelash growth, widely incorporated into numerous beauty products.

顺序

Myr-Lys-Leu-Ala-Lys-Lys-NH2

CAS 号

959610-30-1

分子式

C41H81N9O6

分子量

796.16

Myristoyl Pentapeptide-17 Related Research

1.Primary Biological Mechanisms

Improved delivery efficiency of KGF(Keratinocyte Growth Factor), VEGF(Vascular Endothelial Growth Factor)lysophosphatidic acid (LPA) is facilitated within these cells, prolonging the hair growth cycle.

Anti-inflammatory properties are also exhibited, making it suitable for sparse eyebrows, and as an adjunct treatment of 雄激素性脱发; photoaging around the eyes being a primary concern.

Promoting follicular blood circulation is another key effectenhanced blood flow to the hair follicles means increased nutrient and oxygen delivery, creating an ideal nutritional environment for eyelash growth.

2.Upregulation of keratin 基因表达

The active fragment mentioned above retains the core function of the original KAP proteins(Keratin Associated Proteins).

Binding to cationic amino acid transporters, transcription and subsequent synthesis of KAP5-1 and Type I keratins (31 being the most well documented) is upregulated.

Thickening of the hair shaft cortex is the physical manifestation of this process, eyelash resilience being significantly increased.

3.Promoting microcirculation/nutrient supply

Myristoyl pentapeptide-17 stimulates 角质形成细胞 to release VEGF-Abasic fibroblast growth factors(bFGF or FGF2).

Rapid membrane penetration leads to dermal microvessel vasodilation, improved blood flow, enhanced intercellular nutrient exchange and increased nutrient supply to the follicle.

Anti-inflammatory effects are all part of a larger, self-sustaining process of skin barrier repair.

Shortening the resting phase of the hair follicle and promoting eyelash health, is the end result of Myristoyl Pentapeptide-17’s actions.

COA

高效液相色谱法

多发性硬化症

顺序:

Myr-Lys-Leu-Ala-Lys-Lys-NH2

中科院:

959610-30-1

分子量:

796.14 克/摩尔

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