SYN-AKE is a synthetic peptide that mimics the activity of the snake toxin venom of Waglerin I.Additionally, it is also known as a snake venom peptide or snake-venom-based tripeptide (Glu-Val-Trp) .
विशेष रूप से, it can interact with the body’s natural processes and selectively bind to muscle-type nicotinic acetylcholine receptors. नतीजतन, this inhibits the transmission of acetylcholine (आक) signals and blocks the contraction of the neuromuscular junction (एनएमजे).फलस्वरूप, this causes the instant minimization of the generation of wrinkles and smile lines.Moreover, SYN-AKE has been subjected to clinical trials and proven quite safe and bioactive.
अनुक्रम
H-bAla-Pro-Dab-NHBn
सीएएस संख्या
823202-98-8
आण्विक सूत्र
C19H29N5O3
आणविक वजन
495.6 जी/मोल
1.What Is SYN-AKE
SYN-AKE can act on एसिटाइलकोलाइन रिसेप्टर्स में muscle cells, effectively interfering with the binding of न्यूरोट्रांसमीटर और रिसेप्टर.This local process is safer and more comfortable than botulinum toxin 1 and can significantly improve dynamic wrinkles caused by repeated muscle contraction.
2.Research Findings On SYN-AKE
(1).In vitro studies
शोध के अनुसार,in vitro studies have shown that SYN-AKE’s IC50(half maximal inhibitory concentration) for human nAChRs(Nicotinic acetylcholine receptor) है 0.18 माइक्रोन, which is notably 70% of the concentration of the natural Waglerin-1.Furthermore, कृत्रिम परिवेशीय, low concentrations of SYN-AKE were found to reduce the skin’s response to electrical muscle stimulation द्वारा 62%, which directly proves its ability to inhibit muscle contraction.
(2).Clinical Study on Crow’s Feet
Researchers conducted a double-blind study by recruiting 33 women who with moderate to severe crow ‘s feet.Participants applied a skincare product containing 0.01% SYN-AKE.After one month, measurements using high-resolution optical profilometry showed a significant 32% reduction in wrinkle depth and a 27% decrease in wrinkle volume (P=0.007) compared to the placebo group
इसके अतिरिक्त,researchers evaluated that 82% of the participants had visible improvements in their skin wrinkles, and there were no adverse reactions such as redness, peeling, or itching. This further proves the safety and effectiveness of SYN-AKE.
(3).Synergistic Anti-Aging Effects
In another study, researchers proved that SYN-AKE can combine with MYMD-1 to achieve a dual anti-aging effect.
This study shows that SYN-AKE-MYMD can :
- झुर्रियाँ कम करें
- promote skin whitening in vitro
- inhibit inflammation
इसके अतिरिक्त, it prevents cells from releasing reactive oxygen species that damage DNA, thereby protecting telomerase and achieving a comprehensive anti-aging effect.
सीओए
एचपीएलसी
एमएस





