Myristoyl Pentapeptide-17

Myristoylpentapeptide-17

Myristoylpentapeptide-17

Myristoyl pentapeptide-17 is a bioactive peptide specifically designed and synthesized to address the insufficient growth of natural eyelashes/hair.

 

 

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Myristoyl pentapeptide-17 is a bioactive peptide specifically designed and synthesized to address the insufficient growth of natural eyelashes/hair.

Derived from a 14-18 aminozuur fragment of human keratin-associated protein KAP5-1, it undergoes N-terminal myristoylatie and C-terminal amidation; this enhances its half-life, allowing for direct penetration of human epidermal celmembranen.

Myristoyl pentapeptide-17 is currently one of the more potent cosmetic peptides used to stimulate eyelash growth, widely incorporated into numerous beauty products.

Reeks

Myr-Lys-Leu-Ala-Lys-Lys-NH2

CAS-nummer

959610-30-1

Moleculaire formule

C41H81N9O6

Moleculair gewicht

796.16

Myristoyl Pentapeptide-17 Related Research

1.Primary Biological Mechanisms

Improved delivery efficiency of KGF(Keratinocyte Growth Factor), VEGF(Vascular Endothelial Growth Factor) En lysophosphatidic acid (LPA) is facilitated within these cells, prolonging the hair growth cycle.

Anti-inflammatory properties are also exhibited, making it suitable for sparse eyebrows, and as an adjunct treatment of androgenetische alopecia; fotograferen around the eyes being a primary concern.

Promoten follicular blood circulation is another key effectenhanced blood flow to the hair follicles means increased nutrient and oxygen delivery, creating an ideal nutritional environment for eyelash growth.

2.Opregulatie van keratine genexpressie

The active fragment mentioned above retains the core function of the original KAP proteins(Keratin Associated Proteins).

Binding to cationic amino acid transporters, transcription and subsequent synthesis of KAP5-1 and Type I keratins (31 being the most well documented) is upregulated.

Thickening of the hair shaft cortex is the physical manifestation of this process, eyelash resilience being significantly increased.

3.Promoten microcirculation/nutrient supply

Myristoyl pentapeptide-17 stimulates keratinocyten to release VEGF-A En basic fibroblast growth factors(bFGF or FGF2).

Rapid membrane penetration leads to dermal microvessel vasodilation, improved blood flow, versterkt intercellular nutrient exchange and increased nutrient supply to the follicle.

Anti-inflammatory effects are all part of a larger, self-sustaining process of skin barrier repair.

Shortening the resting phase of the hair follicle and promoting eyelash health, is the end result of Myristoyl Pentapeptide-17’s actions.

COA

HPLC

MEVROUW

Reeks:

Myr-Lys-Leu-Ala-Lys-Lys-NH2

CAS:

959610-30-1

M.W:

796.14 g/mol

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