Trifluoroacetyl tripeptide-2 is an active tripeptide derived from an elastase inhibitor.
Excellent emulsifying, dispersing, antistatic, spreading, and wetting properties are all exhibited by this peptide.
Its natural origin prevents any form of residue from damaging the skin’s protective barrier; thus making it a suitable long-term cosmetic active peptide.
The strong negative charge introduced through trifluoromethylation significantly enhances lipophilicity – rapid penetration across the stratum corneum being one of the primary benefits observed, along with improved overall peptide stability (half life in particular).
序列
{Tfa}-Val-Tyr-Val
化学文摘社编号
64577-63-5
分子式
C21H28F3N3O6
分子量
475.47
Trifluoroacetyl Tripeptide-2 Related Research
1.Matrix Metalloproteinase Inhibition and Tissue Preservation
Inhibiting excessive production and subsequent activation of matrix metalloproteinases is its key action; collagen, elastin and hyaluronic acid degradation within the extracellular matrix of dermal cells is reduced.
Preservation of dermal tissue integrity and density is the end result, age related laxity and other aging effects being effectively alleviated.
Recent studies point to creating a more stable environment for fibroblasts, dynamic equilibrium between synthesis and degradation being maintained.
2.Inhibiting MMP Synthesis
Trifluoroacetyl Tripeptide-2 acts at the upstream level of pro-inflammatory signaling, blocking the overactivation of these pathways.
Excessive MMP production (UV being a prime example) is curtailed.
Quantity and density of the extracellular matrix can be restored – the collagen/elastin network specifically being a primary focus of anti-aging research.
3.Improving all round skin condition
Restoring the turnover metabolism of both collagen and elastic fibers is what the peptide is capable of achieving.
Damage to the dermal support structure can be repaired.
Skin that was once ‘sagging’ or hollowed out, regains its former support.
Skin firmness and elasticity will always be influenced by the actions of this tripeptide.
COA
高效液相色谱法
MS






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